Following is a list of active ingredients for various PMS medications:
| Acetaminophen | Caffeine | Ibuprofen | Pamabrom | Pyrilamine maleate | |
| AAP- Approved* | AAP-Approved* | AAP-Approved* | |||
| Midol Menstrual Complete | 500 mg | 60 mg | - | - | 15 mg |
| Midol Pre-Menstrual Syndrome | 500 mg | - | - | 25 mg | 15 mg |
| Midol Cramp & Body Aches | - | - | 200 mg | - | - |
| Midol Teen Formula | 500 mg | - | - | 25 mg | - |
| Pamprin Multi-Symptom | 500 mg | - | - | 25 mg | 15 mg |
| Premsyn PMS | 500 mg | - | - | 25 mg | 15 mg |
| * Per the AAP Policy Statement The Transfer of Drugs and Other Chemicals Into Human Milk, revised September 2001. Sources:
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Acetaminophen and ibuprofen (pain relievers) and caffeine (a stimulant) are all approved by the AAP for use in breastfeeding mothers.
The other two drugs - pamabrom and pyrilamine maleate - are diuretics.
I have been unable to locate specific information regarding pyrilamine with regards to breastfeeding, but this medication is an antihistamine used directly in pediatrics (in some pediatric cold medications).
Pamabrom is a very mild diuretic - many pharmacists and lactation professionals consider small amounts of this drug to be safe for nursing mothers.
